Ipamorelin: Why a 1998 Paper Called It "The First Selective" One
Ipamorelin earned its place in the literature by being specific: researchers designed it to act on one pathway, as the 1998 paper describes.
What the molecule is
Ipamorelin is a synthetic pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2. PubChem lists it as C38H49N9O5, 711.9 g/mol (PubChem CID 9831659). It includes non-natural residues (Aib, D-2-naphthylalanine), so mass-spec identity on the COA is worth checking.
What the literature studies
The founding paper, Raun et al. 1998 in the European Journal of Endocrinology, titled it "the first selective growth hormone secretagogue" (PMID 9849822). The authors characterized GH release in primary rat pituitary cells in vitro and in animal models (rats and swine). They compared it with GHRP-6 and reported that it was selective, with no comparable effect on ACTH or cortisol in their animal models. It's a well-defined pharmacology tool for receptor-selectivity experiments.
Storing the lyophilized powder
Keep vials sealed, cold, dry, and protected from light, and let them warm to room temperature before opening.
Reading the COA
Confirm the expected mass (about 711.9) and check that the method and lab are named. Supplier COA available; report codes are catalog references.
Why order today
- Ipamorelin 10 mg, lyophilized: $75
- US shipping. Free shipping on orders of $250 or more. Add any other item to your cart to reach free shipping.
- Supplier COA available; report codes are catalog references. 21+ only.
Sources: PubChem CID 9831659; PMID 9849822.
Research Use Only. Sold for in vitro laboratory research. Not for human or veterinary use. 21+.